Last updated: March 2026
How Much Does Ketamine Therapy Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| IV Ketamine Infusion (single session) | $400 – $800 | $400 – $800 |
| IV Ketamine Series (6 sessions) | $2,400 – $4,800 | $2,400 – $4,800 |
| Spravato (esketamine) Session | $600 – $2,000 | $200 – $500 |
| At-Home Ketamine Lozenges (monthly) | $200 – $500 | $200 – $500 |
CPT/ADA Code: 96365, S0012
What Affects the Cost
- Provider credentials and experience
- In-person vs. telehealth sessions
- Session length (30, 45, or 60 minutes)
- In-network vs. out-of-network
- Geographic location (major cities cost more)
- Type of therapy or treatment approach
Insurance Coverage
Typical coverage: IV ketamine infusions are rarely covered by insurance. Spravato (esketamine nasal spray) is FDA-approved and covered by many plans for treatment-resistant depression.
Under the ACA and Mental Health Parity Act, insurance must cover mental health treatment at the same level as physical health. In-network copays are $20-$75 per session. Out-of-network providers may be reimbursed at 50-70%. Many plans now cover telehealth therapy at $0 copay.
How to Save Money
- Online therapy platforms (BetterHelp, Talkspace) cost $60-$100/session
- Open Path Collective: $30-$80/session ($65 lifetime membership)
- Sliding-scale therapists adjust fees based on income
- University training clinics offer $10-$30/session
- Community mental health centers provide low-cost services
- Ask about out-of-network reimbursement from your insurance
Related Procedures & Costs
Frequently Asked Questions
IV ketamine infusions are generally not covered by insurance. Spravato (esketamine nasal spray) is FDA-approved and covered by many plans for treatment-resistant depression with prior authorization.
Many patients experience significant improvement within hours to days, compared to weeks for traditional antidepressants. Effects of a single infusion last 1 to 3 weeks.
A typical initial series is 6 IV infusions over 2 to 3 weeks. Maintenance infusions every 2 to 6 weeks may be needed to sustain benefits.