Last updated: March 2026
How Much Does Zepbound (Tirzepatide) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Zepbound 2.5mg (starter) | $550 – $1,060 | $25 – $250 |
| Zepbound 5mg | $1,060 – $1,060 | $25 – $350 |
| Zepbound 10mg | $1,060 – $1,060 | $25 – $400 |
| Zepbound 15mg (max dose) | $1,060 – $1,060 | $25 – $500 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Varies; many plans cover with prior auth for BMI ≥30
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
List price is $1,059.87/month. LillyDirect vials start at $399/month. Compounded tirzepatide via telehealth costs $199-$499/month.
Many commercial plans cover with prior authorization for BMI ≥30 (or ≥27 with comorbidities). Medicare does not cover weight loss drugs. Copays range $25-$500/month.
Lilly Savings Card ($25/mo with insurance), LillyDirect vials ($399/mo), compounded tirzepatide ($199-$499/mo), or Lilly Cares patient assistance (free if qualifying).