Last updated: March 2026

How Much Does Xeljanz (Tofacitinib) Cost?

Without Insurance
$4,800 – $5,500
Average: $5,150
With Insurance
$300 – $1,400
Average: $850
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Cost Breakdown by Type

Type / Procedure Without Insurance With Insurance
Xeljanz 5mg Tablets $4,800 – $5,500 $300 – $1,400
Xeljanz XR 11mg $4,800 – $5,500 $300 – $1,400

What Affects the Cost

  • Brand-name vs. generic availability
  • Insurance formulary tier placement
  • Pharmacy choice (retail vs. mail-order vs. Costco)
  • Manufacturer savings cards and coupons
  • Dosage and quantity prescribed
  • Geographic location

Insurance Coverage

Typical coverage: Specialty tier — oral JAK inhibitor; prior authorization and step therapy required

Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.

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How to Save Money

  • Always ask for generic when available — saves 50-90%
  • Use GoodRx, RxSaver, or similar discount cards
  • Costco pharmacy is open to non-members and often has lowest prices
  • Mark Cuban's Cost Plus Drugs offers transparent low pricing
  • Manufacturer patient assistance programs provide free medication to qualifying patients
  • HSA/FSA funds can cover medication costs tax-free

Related Procedures & Costs

Frequently Asked Questions

Xeljanz costs $4,800 to $5,500 per month without insurance. Copay assistance programs are available for eligible patients.

Xeljanz treats rheumatoid arthritis, psoriatic arthritis, ulcerative colitis, and polyarticular course juvenile idiopathic arthritis.

Xeljanz carries a boxed warning for increased risk of serious infections, blood clots, and cardiovascular events. Discuss risks with your doctor.

Disclaimer: Costs shown are estimates based on national averages and may vary by location, provider, and insurance plan. This information is for educational purposes only and is not medical advice. Consult your healthcare provider and insurance company for exact costs. Read full disclaimer.
Sources: FAIR Health Consumer, Healthcare Bluebook, CMS Medicare Fee Schedules, GoodRx, and published clinical pricing data. Last updated: 2026-03-15.