Last updated: March 2026

How Much Does Vyvanse (Lisdexamfetamine) Cost?

Without Insurance
$300 – $400
Average: $350
With Insurance
$30 – $80
Average: $55
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Cost Breakdown by Type

Type / Procedure Without Insurance With Insurance
Vyvanse 30mg Capsule (brand) $300 – $380 $30 – $70
Vyvanse 50mg Capsule (brand) $320 – $400 $30 – $80
Lisdexamfetamine 30mg (generic) $150 – $250 $15 – $50

What Affects the Cost

  • Brand-name vs. generic availability
  • Insurance formulary tier placement
  • Pharmacy choice (retail vs. mail-order vs. Costco)
  • Manufacturer savings cards and coupons
  • Dosage and quantity prescribed
  • Geographic location

Insurance Coverage

Typical coverage: Tier 2–3 brand — prior authorization common; generic available in 2023

Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.

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How to Save Money

  • Always ask for generic when available — saves 50-90%
  • Use GoodRx, RxSaver, or similar discount cards
  • Costco pharmacy is open to non-members and often has lowest prices
  • Mark Cuban's Cost Plus Drugs offers transparent low pricing
  • Manufacturer patient assistance programs provide free medication to qualifying patients
  • HSA/FSA funds can cover medication costs tax-free

Related Procedures & Costs

Frequently Asked Questions

Brand-name Vyvanse costs $300 to $400 per month without insurance. Generic lisdexamfetamine is now available at $150 to $250.

Yes, generic lisdexamfetamine became available in 2023, offering significant savings over brand-name Vyvanse.

Vyvanse (lisdexamfetamine) is a prodrug that must be converted in the body, providing smoother onset and lower abuse potential. It lasts up to 14 hours compared to Adderall XR's 10-12 hours.

Disclaimer: Costs shown are estimates based on national averages and may vary by location, provider, and insurance plan. This information is for educational purposes only and is not medical advice. Consult your healthcare provider and insurance company for exact costs. Read full disclaimer.
Sources: FAIR Health Consumer, Healthcare Bluebook, CMS Medicare Fee Schedules, GoodRx, and published clinical pricing data. Last updated: 2026-03-15.