Last updated: March 2026

How Much Does Tiotropium (Spiriva) Cost?

Without Insurance
$300 – $500
Average: $400
With Insurance
$30 – $80
Average: $55
Advertisement

Cost Breakdown by Type

Type / Procedure Without Insurance With Insurance
Spiriva HandiHaler 18mcg (capsules) $300 – $450 $30 – $70
Spiriva Respimat 2.5mcg (inhaler) $350 – $500 $35 – $80

What Affects the Cost

  • Brand-name vs. generic availability
  • Insurance formulary tier placement
  • Pharmacy choice (retail vs. mail-order vs. Costco)
  • Manufacturer savings cards and coupons
  • Dosage and quantity prescribed
  • Geographic location

Insurance Coverage

Typical coverage: Tier 2–3 brand — no generic available; copay cards may help reduce cost

Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.

Advertisement

How to Save Money

  • Always ask for generic when available — saves 50-90%
  • Use GoodRx, RxSaver, or similar discount cards
  • Costco pharmacy is open to non-members and often has lowest prices
  • Mark Cuban's Cost Plus Drugs offers transparent low pricing
  • Manufacturer patient assistance programs provide free medication to qualifying patients
  • HSA/FSA funds can cover medication costs tax-free

Related Procedures & Costs

Frequently Asked Questions

Spiriva costs between $300 and $500 per month without insurance. There is currently no generic alternative available in the US.

Spiriva (tiotropium) is a long-acting anticholinergic bronchodilator used for maintenance treatment of COPD and long-term asthma control in patients 6 years and older.

There is no FDA-approved generic for Spiriva currently. The manufacturer offers copay savings programs for eligible patients to reduce out-of-pocket costs.

Disclaimer: Costs shown are estimates based on national averages and may vary by location, provider, and insurance plan. This information is for educational purposes only and is not medical advice. Consult your healthcare provider and insurance company for exact costs. Read full disclaimer.
Sources: FAIR Health Consumer, Healthcare Bluebook, CMS Medicare Fee Schedules, GoodRx, and published clinical pricing data. Last updated: 2026-03-15.