Last updated: March 2026
How Much Does Skyrizi (Risankizumab) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Skyrizi 150mg Subcutaneous | $15,000 – $18,000 | $500 – $3,000 |
| Skyrizi 600mg IV (Crohn's induction) | $30,000 – $36,000 | $1,500 – $6,000 |
CPT/ADA Code: J3590
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Specialty tier — prior authorization required; dosed every 12 weeks for psoriasis
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Skyrizi costs $15,000 to $18,000 per injection without insurance. For psoriasis, it is given every 12 weeks after initial loading doses.
Skyrizi treats moderate-to-severe plaque psoriasis, psoriatic arthritis, and Crohn's disease.
Yes, the Skyrizi Complete savings card may reduce costs to as low as $5 per dose for eligible commercially insured patients.