Last updated: March 2026
How Much Does Sitagliptin (Januvia) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Sitagliptin 100mg Generic | $10 – $30 | $5 – $15 |
| Januvia 100mg (brand) | $400 – $500 | $30 – $60 |
| Janumet 50/1000mg (brand combo) | $450 – $550 | $35 – $70 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Tier 2-3 — brand Januvia is expensive; generic sitagliptin available at much lower cost since 2023
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Brand Januvia costs $400 to $500 per month without insurance. However, generic sitagliptin became available in 2023 and costs only $10 to $30 per month, making it dramatically more affordable.
Yes, generic sitagliptin was approved and launched in 2023. It is the same medication at a fraction of the cost, typically $10 to $30 per month without insurance.
Sitagliptin is a DPP-4 inhibitor that helps lower blood sugar by increasing insulin release and decreasing glucagon after meals. It has a low risk of hypoglycemia and is weight-neutral.