Last updated: March 2026
How Much Does Rituximab (Rituxan) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| 1000mg IV Infusion (single dose) | $5,000 – $10,000 | $100 – $1,000 |
| Treatment Course (2 infusions) | $10,000 – $20,000 | $200 – $2,000 |
| Biosimilar (per infusion) | $3,000 – $7,000 | $50 – $800 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Specialty Tier 5; covered under medical benefit; prior auth required
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Brand Rituxan costs $5,000 to $10,000 per infusion. A typical RA course of 2 infusions costs $10,000 to $20,000. Biosimilars are 20-40% cheaper.
Rituximab treats rheumatoid arthritis, certain lymphomas, chronic lymphocytic leukemia, and autoimmune conditions like vasculitis and pemphigus.
For RA, two 1000mg infusions are given 2 weeks apart, repeated every 6 to 12 months. Cancer protocols vary.