Last updated: March 2026
How Much Does Repatha (Evolocumab) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Repatha 140mg Every 2 Weeks | $450 – $600 | $25 – $200 |
| Repatha 420mg Monthly | $500 – $700 | $25 – $200 |
| Repatha Pushtronex System | $500 – $700 | $25 – $200 |
CPT/ADA Code: J3590
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Specialty tier — PCSK9 inhibitor; prior authorization and step therapy required
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Repatha costs $450 to $700 per month without insurance. Amgen offers a copay card that may reduce costs to $5 per month.
Repatha lowers LDL cholesterol in patients with familial hypercholesterolemia or atherosclerotic cardiovascular disease who need additional LDL reduction beyond statins.
Repatha can lower LDL cholesterol by 50-60% when added to statin therapy and has been proven to reduce heart attacks and strokes.