Last updated: March 2026
How Much Does Praluent (Alirocumab) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Praluent 75mg Every 2 Weeks | $450 – $600 | $25 – $200 |
| Praluent 150mg Every 2 Weeks | $500 – $700 | $25 – $200 |
| Praluent 300mg Monthly | $500 – $700 | $25 – $200 |
CPT/ADA Code: J0222
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Specialty tier — PCSK9 inhibitor; prior authorization and step therapy required
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Praluent costs $450 to $700 per month without insurance. PCSK9 inhibitor prices have decreased significantly in recent years.
Praluent dramatically lowers LDL cholesterol for patients who cannot achieve adequate control with statins alone, and reduces cardiovascular event risk.
Insurance coverage typically requires prior authorization and documented failure of maximum-dose statin therapy. Coverage has improved as prices have decreased.