Last updated: March 2026
How Much Does Nystatin Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Oral Suspension 100,000 units/mL (60mL) | $10 – $35 | $0 – $15 |
| Topical Cream 100,000 units/g (30g) | $10 – $30 | $0 – $10 |
| Oral Pastilles (Troches) | $15 – $50 | $5 – $15 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Covered as Tier 1 generic on most formularies
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Nystatin treats fungal infections including oral thrush (mouth), skin candidiasis, and vaginal yeast infections. It works by disrupting fungal cell membranes.
Generic nystatin suspension costs $10 to $35 and the cream costs $10 to $30 without insurance at most pharmacies.
Yes, nystatin oral suspension is commonly prescribed for oral thrush in infants and is considered safe.