Last updated: March 2026
How Much Does Mupirocin (Bactroban) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Mupirocin 2% Ointment (22g) | $10 – $25 | $3 – $8 |
| Mupirocin 2% Cream (15g) | $15 – $40 | $5 – $12 |
| Mupirocin 2% Nasal Ointment | $15 – $35 | $5 – $12 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Tier 1–2 generic — covered for bacterial skin infections
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Mupirocin costs $10 to $40 without insurance depending on the formulation and size. It is available as an affordable generic.
Mupirocin is a topical antibiotic used to treat impetigo, minor skin infections, and MRSA nasal colonization. It is effective against staph and strep bacteria.
No, mupirocin requires a prescription. It is a topical antibiotic, and inappropriate use can contribute to antibiotic resistance.