Last updated: March 2026
How Much Does Medroxyprogesterone (Provera) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Medroxyprogesterone 10mg Tablet | $4 – $15 | $0 – $5 |
| Medroxyprogesterone 150mg/mL Injection (Depo-Provera) | $50 – $100 | $0 – $30 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Tier 1 generic — widely covered; used for menstrual disorders and as contraceptive injection
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Medroxyprogesterone tablets cost $4 to $20 for a 30-day supply. The Depo-Provera injection costs $50 to $100 per shot without insurance.
Medroxyprogesterone tablets treat irregular periods, abnormal uterine bleeding, and amenorrhea. The injectable form (Depo-Provera) is used as a contraceptive given every 3 months.
Common side effects of the injection include weight gain, irregular bleeding, headaches, and mood changes. Long-term use may affect bone density.