Last updated: March 2026
How Much Does Levofloxacin Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Levofloxacin 250mg (generic) | $8 – $18 | $2 – $8 |
| Levofloxacin 500mg (generic) | $8 – $25 | $3 – $10 |
| Levofloxacin 750mg (generic) | $10 – $30 | $4 – $12 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Tier 1-2 generic — fluoroquinolone with boxed warnings; reserved for serious infections
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Generic levofloxacin costs $8 to $30 for a typical course without insurance. Shorter high-dose regimens (750mg x 5 days) may be more cost-effective than longer courses.
Levofloxacin treats community-acquired pneumonia, complicated UTIs, sinusitis, and chronic bronchitis exacerbations. Due to boxed warnings, it is now reserved for infections with no safer alternative.
Both carry the same FDA boxed warnings for tendon rupture and nerve damage. Levofloxacin has broader gram-positive coverage, while ciprofloxacin is preferred for certain gram-negative infections.