Last updated: March 2026
How Much Does Erythromycin Topical Gel Cost?
Without Insurance
$20 – $80
Average: $50
With Insurance
$0 – $20
Average: $10
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Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| 2% Gel Generic (30g) | $20 – $50 | $0 – $15 |
| 2% Solution Generic (60mL) | $25 – $60 | $5 – $15 |
| Erythromycin/Benzoyl Peroxide Gel (Benzamycin) | $40 – $80 | $10 – $20 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Covered as Tier 2 generic on most plans
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
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How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Topical erythromycin treats mild-to-moderate acne. Like clindamycin, it should be used with benzoyl peroxide.
Generic erythromycin gel costs $20 to $60 per tube.
Clindamycin is generally preferred as it is more effective against acne bacteria. Erythromycin is an alternative for those who cannot use clindamycin.
Disclaimer: Costs shown are estimates based on national averages and may vary by location, provider, and insurance plan. This information is for educational purposes only and is not medical advice. Consult your healthcare provider and insurance company for exact costs. Read full disclaimer.
Sources: FAIR Health Consumer, Healthcare Bluebook, CMS Medicare Fee Schedules, GoodRx, and published clinical pricing data. Last updated: 2026-03-15.