Last updated: March 2026
How Much Does Dupixent (Dupilumab) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Dupixent 300mg Prefilled Syringe | $3,600 – $4,200 | $200 – $1,200 |
| Dupixent 200mg Pediatric | $3,600 – $4,200 | $200 – $1,200 |
CPT/ADA Code: J0881
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Specialty tier — prior authorization and step therapy often required
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Dupixent treats moderate-to-severe eczema (atopic dermatitis), asthma, chronic rhinosinusitis with nasal polyps, and eosinophilic esophagitis.
Without insurance, Dupixent costs approximately $3,600 to $4,200 per month. With insurance and copay cards, patients may pay as little as $0-$200 per month.
Yes, the Dupixent MyWay copay card can reduce out-of-pocket costs to as low as $0 per month for eligible commercially insured patients.