Last updated: March 2026
How Much Does Dapsone (Aczone) Cost?
Without Insurance
$15 – $500
Average: $258
With Insurance
$0 – $60
Average: $30
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Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| 25-100mg Oral Tablets Generic (30-day) | $15 – $50 | $0 – $15 |
| Aczone 7.5% Topical Gel (60g) | $300 – $500 | $30 – $60 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Oral generic Tier 1; topical Aczone Tier 3-4
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
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How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Oral dapsone treats dermatitis herpetiformis, leprosy, and certain other skin conditions. Topical dapsone (Aczone) treats acne.
Topical Aczone gel costs $300 to $500 without insurance. Oral dapsone is much cheaper at $15 to $50/month.
Yes, oral dapsone requires regular CBC monitoring as it can cause hemolytic anemia, especially in patients with G6PD deficiency.
Disclaimer: Costs shown are estimates based on national averages and may vary by location, provider, and insurance plan. This information is for educational purposes only and is not medical advice. Consult your healthcare provider and insurance company for exact costs. Read full disclaimer.
Sources: FAIR Health Consumer, Healthcare Bluebook, CMS Medicare Fee Schedules, GoodRx, and published clinical pricing data. Last updated: 2026-03-15.