Last updated: March 2026
How Much Does Clindamycin Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Clindamycin 150mg (generic) | $8 – $18 | $2 – $8 |
| Clindamycin 300mg (generic) | $8 – $25 | $3 – $10 |
| Clindamycin 1% Topical Gel (generic) | $15 – $40 | $5 – $15 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Tier 1-2 generic — effective against MRSA and anaerobes; penicillin allergy alternative
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Generic oral clindamycin costs $8 to $30 for a typical course without insurance. Topical formulations for acne may cost $15 to $40.
Clindamycin treats skin infections (including MRSA), bone infections, dental infections, pelvic infections, and is used topically for acne. It is a key alternative for penicillin-allergic patients.
Yes, clindamycin carries a higher risk of Clostridioides difficile infection than many other antibiotics. Report persistent diarrhea during or after treatment to your doctor immediately.