Last updated: March 2026

How Much Does Canagliflozin (Invokana) Cost?

Without Insurance
$500 – $550
Average: $525
With Insurance
$30 – $150
Average: $90
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Cost Breakdown by Type

Type / Procedure Without Insurance With Insurance
Invokana 100mg (brand) $500 – $530 $30 – $100
Invokana 300mg (brand) $500 – $550 $30 – $120
Invokamet 150/1000mg (brand combo) $550 – $650 $40 – $150

What Affects the Cost

  • Brand-name vs. generic availability
  • Insurance formulary tier placement
  • Pharmacy choice (retail vs. mail-order vs. Costco)
  • Manufacturer savings cards and coupons
  • Dosage and quantity prescribed
  • Geographic location

Insurance Coverage

Typical coverage: Tier 3 brand — SGLT2 inhibitor with kidney protection benefits; prior authorization common

Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.

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How to Save Money

  • Always ask for generic when available — saves 50-90%
  • Use GoodRx, RxSaver, or similar discount cards
  • Costco pharmacy is open to non-members and often has lowest prices
  • Mark Cuban's Cost Plus Drugs offers transparent low pricing
  • Manufacturer patient assistance programs provide free medication to qualifying patients
  • HSA/FSA funds can cover medication costs tax-free

Related Procedures & Costs

Frequently Asked Questions

Invokana costs $500 to $550 per month without insurance. With insurance, copays range from $30 to $150 depending on your plan tier.

Yes, the CREDENCE trial showed canagliflozin significantly reduces the risk of kidney failure in patients with type 2 diabetes and chronic kidney disease.

Canagliflozin carries a slightly increased risk of lower limb amputations and bone fractures compared to other SGLT2 inhibitors. Your doctor will assess your individual risk factors.

Disclaimer: Costs shown are estimates based on national averages and may vary by location, provider, and insurance plan. This information is for educational purposes only and is not medical advice. Consult your healthcare provider and insurance company for exact costs. Read full disclaimer.
Sources: FAIR Health Consumer, Healthcare Bluebook, CMS Medicare Fee Schedules, GoodRx, and published clinical pricing data. Last updated: 2026-03-15.