Last updated: March 2026

How Much Does Benzoyl Peroxide Rx Cost?

Without Insurance
$8 – $30
Average: $19
With Insurance
$0 – $10
Average: $5
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Cost Breakdown by Type

Type / Procedure Without Insurance With Insurance
Benzoyl Peroxide 5% Gel (Rx, 60g) $8 – $20 $0 – $8
Benzoyl Peroxide 10% Wash (Rx) $10 – $25 $3 – $10
Benzoyl Peroxide/Clindamycin Gel (Duac generic) $30 – $80 $10 – $30

What Affects the Cost

  • Brand-name vs. generic availability
  • Insurance formulary tier placement
  • Pharmacy choice (retail vs. mail-order vs. Costco)
  • Manufacturer savings cards and coupons
  • Dosage and quantity prescribed
  • Geographic location

Insurance Coverage

Typical coverage: Tier 1–2 — covered for acne treatment; many OTC options also available

Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.

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How to Save Money

  • Always ask for generic when available — saves 50-90%
  • Use GoodRx, RxSaver, or similar discount cards
  • Costco pharmacy is open to non-members and often has lowest prices
  • Mark Cuban's Cost Plus Drugs offers transparent low pricing
  • Manufacturer patient assistance programs provide free medication to qualifying patients
  • HSA/FSA funds can cover medication costs tax-free

Related Procedures & Costs

Frequently Asked Questions

Prescription benzoyl peroxide products cost $8 to $30 without insurance. Combination products with antibiotics cost more, around $30 to $80.

Prescription versions may offer unique formulations, combination products with antibiotics, or better insurance coverage. Your dermatologist can recommend the best option for your skin.

Studies show 2.5% to 5% is as effective as 10% with less irritation. Higher concentrations mainly cause more dryness without significantly better acne clearing.

Disclaimer: Costs shown are estimates based on national averages and may vary by location, provider, and insurance plan. This information is for educational purposes only and is not medical advice. Consult your healthcare provider and insurance company for exact costs. Read full disclaimer.
Sources: FAIR Health Consumer, Healthcare Bluebook, CMS Medicare Fee Schedules, GoodRx, and published clinical pricing data. Last updated: 2026-03-15.