Last updated: March 2026
How Much Does Azathioprine (Imuran) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| 50mg Tablets Generic (30-day) | $15 – $50 | $0 – $15 |
| 75-150mg Daily (30-day) | $25 – $80 | $5 – $20 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Covered as Tier 1-2 generic on most plans
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Azathioprine treats autoimmune diseases including rheumatoid arthritis, lupus, inflammatory bowel disease, and prevents organ transplant rejection.
Yes, TPMT/NUDT15 testing is recommended before starting azathioprine to identify patients at risk for severe bone marrow suppression.
Generic azathioprine costs $15 to $80 per month depending on the dose, making it an affordable immunosuppressant.