Last updated: March 2026
How Much Does Apixaban (Eliquis) Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Eliquis 5mg Tablet (60ct) | $500 – $580 | $30 – $80 |
| Eliquis 2.5mg Tablet (60ct) | $500 – $580 | $30 – $80 |
| Apixaban 5mg (generic, when available) | $200 – $350 | $15 – $50 |
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Tier 3 brand — covered with prior authorization; copay card available for commercially insured patients
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Eliquis costs $500 to $600 per month without insurance. The manufacturer's copay card can reduce costs to as low as $10 for commercially insured patients.
Generic apixaban has limited availability. When fully generic, prices are expected to be significantly lower than brand Eliquis.
Eliquis (apixaban) is a direct oral anticoagulant (DOAC) used to prevent stroke in atrial fibrillation and treat/prevent deep vein thrombosis and pulmonary embolism.