Last updated: March 2026
How Much Does Amniocentesis Cost?
Cost Breakdown by Type
| Type / Procedure | Without Insurance | With Insurance |
|---|---|---|
| Genetic Amniocentesis | $1,500 – $4,000 | $200 – $800 |
| Amniocentesis with FISH Testing | $2,000 – $5,000 | $300 – $1,000 |
| Amniocentesis for Lung Maturity | $1,500 – $3,500 | $200 – $700 |
CPT/ADA Code: 59000
What Affects the Cost
- Brand-name vs. generic availability
- Insurance formulary tier placement
- Pharmacy choice (retail vs. mail-order vs. Costco)
- Manufacturer savings cards and coupons
- Dosage and quantity prescribed
- Geographic location
Insurance Coverage
Typical coverage: Diagnostic — covered when indicated by age, screening results, or medical history
Most insurance plans use a tiered formulary: Tier 1 (generic) $0-$15 copay, Tier 2 (preferred brand) $25-$75, Tier 3 (non-preferred brand) $50-$150, Tier 4 (specialty) $100-$500+. Prior authorization may be required for certain medications. Step therapy may require trying cheaper alternatives first.
How to Save Money
- Always ask for generic when available — saves 50-90%
- Use GoodRx, RxSaver, or similar discount cards
- Costco pharmacy is open to non-members and often has lowest prices
- Mark Cuban's Cost Plus Drugs offers transparent low pricing
- Manufacturer patient assistance programs provide free medication to qualifying patients
- HSA/FSA funds can cover medication costs tax-free
Related Procedures & Costs
Frequently Asked Questions
Amniocentesis costs $1,500 to $5,000 without insurance including the procedure and genetic analysis.
Amniocentesis is recommended when screening tests suggest increased risk of chromosomal abnormalities, typically performed at 15-20 weeks of pregnancy.
Amniocentesis carries a small risk of miscarriage (about 0.1-0.3%). Most women experience only mild cramping during the procedure.